Cooperation between the PDGF receptors in cardiac neural crest cell migration.

@article{Richarte2007CooperationBT,
  title={Cooperation between the PDGF receptors in cardiac neural crest cell migration.},
  author={Alicia M Richarte and Holly Mead and Michelle D Tallquist},
  journal={Developmental biology},
  year={2007},
  volume={306 2},
  pages={
          785-96
        }
}
Neural crest cells (NCCs) are essential components of the sympathetic nervous system, skin, craniofacial skeleton, and aortic arch. It has been known for many years that perturbation of migration, proliferation, and/or differentiation of these cells leads to birth defects such as cleft palate and persistent truncus arteriosus (PTA). Previously, we had shown that disruption of the platelet-derived growth factor receptor (PDGFR) alpha in NCCs resulted in defects in craniofacial and aortic arch… CONTINUE READING

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