Cooperation between Magnesium and Metabolite Controls Collapse of the SAM-I Riboswitch.

@article{Roy2017CooperationBM,
  title={Cooperation between Magnesium and Metabolite Controls Collapse of the SAM-I Riboswitch.},
  author={Susmita Roy and Jos{\'e} N. Onuchic and Karissa Y. Sanbonmatsu},
  journal={Biophysical journal},
  year={2017},
  volume={113 2},
  pages={
          348-359
        }
}
The S-adenosylmethionine (SAM)-I riboswitch is a noncoding RNA that regulates the transcription termination process in response to metabolite (SAM) binding. The aptamer portion of the riboswitch may adopt an open or closed state depending on the presence of metabolite. Although the transition between the open and closed states is critical for the switching… CONTINUE READING