Cooperation and competition in the dynamics of tissue architecture during homeostasis and tumorigenesis.

@article{CsikszNagy2013CooperationAC,
  title={Cooperation and competition in the dynamics of tissue architecture during homeostasis and tumorigenesis.},
  author={Attila Csik{\'a}sz-Nagy and Luis M. Escudero and M. Guillaud and Sean Sedwards and B. Baum and Matteo Cavaliere},
  journal={Seminars in cancer biology},
  year={2013},
  volume={23 4},
  pages={
          293-8
        }
}
  • Attila Csikász-Nagy, Luis M. Escudero, +3 authors Matteo Cavaliere
  • Published 2013
  • Biology, Medicine
  • Seminars in cancer biology
  • The construction of a network of cell-to-cell contacts makes it possible to characterize the patterns and spatial organization of tissues. Such networks are highly dynamic, depending on the changes of the tissue architecture caused by cell division, death and migration. Local competitive and cooperative cell-to-cell interactions influence the choices cells make. We review the literature on quantitative data of epithelial tissue topology and present a dynamical network model that can be used to… CONTINUE READING

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