Cooperation Between Kinesin Motors Promotes Spindle Symmetry and Chromosome Organization in Oocytes.

@article{Radford2017CooperationBK,
  title={Cooperation Between Kinesin Motors Promotes Spindle Symmetry and Chromosome Organization in Oocytes.},
  author={Sarah J. Radford and Allysa Marie M Go and Kim S McKim},
  journal={Genetics},
  year={2017},
  volume={205 2},
  pages={
          517-527
        }
}
The oocyte spindle in most animal species is assembled in the absence of the microtubule-organizing centers called centrosomes. Without the organization provided by centrosomes, acentrosomal meiotic spindle organization may rely heavily on the bundling of microtubules by kinesin motor proteins. Indeed, the minus-end directed kinesin-14 NCD, and the plus-end directed kinesin-6 Subito are known to be required for oocyte spindle organization in Drosophila melanogaster How multiple microtubule… CONTINUE READING
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