Ergotismo del sistema nervioso central. Reporte de dos muertes maternas asociadas a vasoespasmo cerebral por medicamentos derivados del ergot en Antioquia, Colombia, y revisión de la literatura
Ergotism of the central nervous system due to the use of drugs such as bromocriptine and methylergonovine must be recognised during the postpartum period because it is life-threatening.
Ergot alkaloids: extent of human and animal exposure
The present review focuses more on how man and animals are exposed to ergot alkaloids than on toxicology and methods of analysis.
Serotonergic and tryptaminergic overstimulation on refeeding implicated in "enlightenment" experiences.
- Biology, PsychologyMedical hypotheses
University of Birmingham Serotonin syndrome
- Psychology, Biology
Whether the inhibition of tryptophan hydroxylase (TPH) may provide an opportunity to pharmacologically target central 5-HT synthesis, and so develop new treatments for severe, life-threatening SS is discussed.
2. Ecstasy and the serotonin syndrome
- Medicine, Psychology
This chapter addresses this complication through an exploration of the theoretical mechanisms and clinical manifestations of this life-threatening pharmacological interaction between SSRIs and MDMA.
Sudor Anglicus: an epidemic targeting the autonomic nervous system
- MedicineClinical Autonomic Research
Of candidate etiologic agents, a virus is most likely, given the seasonal variation, geographic clustering, and pattern of spread of the epidemics, but a definitive match with known viruses has remained elusive.
SHOWING 1-10 OF 31 REFERENCES
Serotonin Syndrome Complicating Migraine Pharmacotherapy
- Medicine, PsychologyCephalalgia : an international journal of headache
Six patients with migraine who developed symptoms suggestive of the serotonin syndrome were reported, five were taking one or more serotomimetic agents for migraine prophylaxis (sertraline, paroxetine, lithium, imipramine, amitriptyline), and in each case the symptoms and signs developed in close temporal proximity with use of a migraine abortive agent known to interact with serotonin receptors.
Historical view on ergot alkaloids.
- Medicine, ChemistryPharmacology
Once a dreaded poison, ergot has changed its role over the centuries to become a rich treasure house of valuable pharmaceuticals, which has resulted in the elucidation of their structures and total syntheses and preparation of valuable therapeutics.
Cerebral ergotism under treatment with ergotamine and ritonavir
- Medicine, PsychologyNeurology
A 37-year-old woman with AIDS was admitted to the authors' stroke unit with an 18-hour history of acute-onset speech disorder and weakness of the right-sided extremities, and her treating physician prescribed ergotamine suppositories, which never were described before.
Localization of 3H‐Dihydroergotamine‐binding sites in the cat central nervous system: Relevance to migraine
- BiologyAnnals of neurology
Using in vitro and ex vivo autoradiographic techniques, the localization of specific binding sites for 3H‐dihydroergotamine in the cat brain has been examined, finding the highest density of binding sites was found in the dorsal and medial raphe nuclei of the midbrain.
THE SUBSTANCE RESPONSIBLE FOR THE TRADITIONAL CLINICAL EFFECT OF ERGOT
- MedicineBritish medical journal
It is interesting to note that a marked change to virilism does not occur in women as the direct result of these lesions after the menopause, although, as the authors know, in many after that epoch certain masculine characteristics, such as hair on the face, are common.
Clinically Significant Drug Interactions with Agents Specific For Migraine Attacks
- Medicine, BiologyCNS drugs
Nearly all the clinically important interactions between the ergopeptide antimigraine agents and currently marketed drugs are likely to have already come to notice.
Ergot Poisoning at Pont St. Esprit
- MedicineBritish medical journal
Patterson found that in his cases a large number of leptospires continued to be excreted in the urine for many weeks after clinical recovery.
Serotonin and Appetite Regulation
- Biology, Psychology
Evidence suggests that serotonergic drugs can continue to play a useful role in the treatment of obesity and whether serotonin-based interventions are appropriate for the binge eating subpopulation of obese people and for those individuals displaying binge eating disorder.
Ergotamine-induced fetal stress: review of side effects of ergot alkaloids during pregnancy.
- MedicineEuropean journal of obstetrics, gynecology, and reproductive biology
Ergot Alkaloids and Related Compounds
- Biology, ChemistryHandbook of Experimental Pharmacology / Handbuch der experimentellen Pharmakologie
I Introduction to the Pharmacology of Ergot Alkaloids and Related Compounds as a Basis of Their Therapeutic Application and theories on the Mechanism of Noradrenaline "Overflow".