Convulsants antagonise inhibition in the olfactory cortex slice

@article{Scholfield1980ConvulsantsAI,
  title={Convulsants antagonise inhibition in the olfactory cortex slice},
  author={Charles N Scholfield},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1980},
  volume={314},
  pages={29-36}
}
The effects of some γ-aminobutyric acid (GABA) antagonists and other “convulsants” have been tested on neurones of the isolated olfactory cortex slice preparation of the guinea-pig using single cell intracellular and gross extracellular recording techniques. Bicuculline, picrotoxin, strychnine, leptazol, bemegride, and also theophylline and d-tubocurarine all increased the duration and amplitude of the excitatory postsynaptic potential, thereby producing a seizure-like discharge. These drugs… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

Local anaesthetics and barbiturates: effect on evoked potentials from olfactory cortex in vitro

  • CN Scholfield, JA Harvey
  • J Pharmacol Exp Ther
  • 1975
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…