Convicting Zika

  title={Convicting Zika},
  author={Peter Doshi},
  journal={British Medical Journal},
  • P. Doshi
  • Published 7 April 2016
  • Medicine
  • British Medical Journal
Scientists are racing to prove that Zika virus has caused the recent spike in cases of microcephaly in Latin America. But, asks Peter Doshi, what might be being overlooked? 
Zika circumnavigates the globe to go for gold
  • P. Griffiths
  • Biology, Medicine
    Reviews in medical virology
  • 2016
Concerns about Zika may bring CMV out from the shadows to reveal its true effects on the population, as well as helping countries mitigate the theoretical risk of importation.
SIR Model of Spread of Zika Virus Infections: ZIKV Linked to Microcephaly Simulations
An SIR model of Zika virus (ZIKV) spread is formulated that includes ZikV infections to newborns and it appears that controlling spread of ZIKV infections by human-mosquito transmission may greatly reduce the value of R0.
Zika Virus Infection as a Cause of Congenital Brain Abnormalities and Guillain–Barré Syndrome: Systematic Review
A rapid and systematic review of the evidence for causality found sufficient evidence to say that Zika virus is a cause of congenital abnormalities and is a trigger of GBS.
Establishing the teratogenicity of Zika and evaluating causal criteria
This paper appeals to the thesis of Russo and Williamson to devise an epistemological framework that can be used to compare and evaluate sets of causal criteria to decide when enough criteria are satisfied to establish causality.


Zika virus and microcephaly: why is this situation a PHEIC?
This poster presents a probabilistic analysis of the immune system’s response to diarrhoea and reveals clear patterns of decline in the immune systems of immune-inflammatory bowel disease and central nervous system disorders.
Zika Virus as a Cause of Neurologic Disorders.
As researchers investigate whether and by what mechanisms Zika virus infections could affect the nervous system, there is a key question for public health: How can currently available evidence about
Zika Virus Infection in Pregnant Women in Rio de Janeiro—Preliminary Report
ZIKV was first identified in Brazil in 2015 by reverse transcriptase–polymerase chain reaction assays of serum specimens from patients who presented with a dengue-like illness that was characterized by rash, fever, myalgias, arthralgias, and conjunctivitis.
Association between Zika virus and microcephaly in French Polynesia, 2013–15: a retrospective study
This work retrospectively analysed data from a Zika virus outbreak in French Polynesia to provide a quantitative estimate of the risk of microcephaly in fetuses and neonates whose mothers are infected with Zika virus.
Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.
First Zika-linked birth defects detected in Colombia
One newborn is diagnosed with microcephaly — an abnormally small head — and two others with congenital brain abnormalities, says Alfonso Rodriguez-Morales, who chairs the Colombian Collaborative Network on Zika (RECOLZIKA), which made the diagnoses.
The Environment and Disease: Association or Causation?
  • A. B. Hill
  • Medicine
    Proceedings of the Royal Society of Medicine
  • 1965
This paper contrasts Bradford Hill’s approach with a currently fashionable framework for reasoning about statistical associations – the Common Task Framework – and suggests why following Bradford Hill, 50+ years on, is still extraordinarily reasonable.
Microcephaly in northeast Brazil: a review of 16 208 births between
  • Bull World Health Organ
  • 2012
For permission to use (where not already granted under a licence
  • permissions For personal use only: See rights and reprints
Guillain-Barre syndrome, and microcephaly. Situation report
  • WHO. Zika virus