Conversion of thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects.

  title={Conversion of thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects.},
  author={L. Braverman and S. Ingbar and K. Sterling},
  journal={The Journal of clinical investigation},
  volume={49 5},
  • L. Braverman, S. Ingbar, K. Sterling
  • Published 1970
  • Medicine
  • The Journal of clinical investigation
  • Studies of the possibility that thyroxine (T4) is converted to 3.5,3'-triiodo-L-thyronine (T3) in the extrathyroidal tissues in man have been conducted in 13 patients, all but two of whom were athyreotic or hypothyroid, and all of whom were receiving at least physiological replacement doses of synthetic sodium-L-thyroxine.T3 was found in the sera of all patients, in concentrations ranging between 243 and 680 ng/100 ml (normal range 170-270 ng/100 ml). These concentrations were far in excess of… CONTINUE READING
    Estimation of thyroxine and triiodothyronine distribution and of the conversion rate of thyroxine to triiodothyronine in man.
    L-Triiodothyronine and L-Reverse-Triiodothyronine Generation in the Human Polymorphonuclear Leukocyte
    • Polymorphonuclear Leukocyte
    • 2013


    Publications referenced by this paper.