Conversion of cysteine to 3-mercaptopyruvic acid by bacterial aminotransferases.


3-Mercaptopyruvate (3MPy), a structural analog of 3-mercaptopropionic acid, is a precursor compound for biosynthesis of polythioesters in bacteria. The cost-effectiveness and sustainability of the whole process could be greatly improved by using the cysteine degradation pathway for an intracellular supply of 3MPy. Transamination of cysteine to its… (More)
DOI: 10.1016/j.enzmictec.2017.01.004