Conversion of Major Ginsenoside Rb1 to Ginsenoside F2 by Caulobacter leidyia

@article{Cheng2006ConversionOM,
  title={Conversion of Major Ginsenoside Rb1 to Ginsenoside F2 by Caulobacter leidyia},
  author={Le-Qin Cheng and Myung Kyum Kim and Jun-Won Lee and Y A Lee and Deok-Chun Yang},
  journal={Biotechnology Letters},
  year={2006},
  volume={28},
  pages={1121-1127}
}
Ginsenoside Rb1 is the most predominant ginsenoside in Panax species (ginseng) and the hydrolysis of this ginsenoside produces pharmaceutically active compounds. Caulobacter leidyia GP45, one of the isolates having strong β-glucosidase-producing activity, converted ginsenoside Rb1 to the active metabolites by 91%. The structures of the resultant metabolites were identified by NMR. Ginsenoside Rb1 had been consecutively converted to ginsenoside Rd (1), F2 (2) and compound K (3) via the… CONTINUE READING