Conversion from cyclosporine to tacrolimus improves renal function and lipid profile after cardiac transplantation.

Abstract

BACKGROUND Calcineurin inhibitors (CNIs) have become the cornerstone of immunosuppressive regimens following heart transplantation, but their use is associated with nephrotoxicity. The impact on renal function after conversion from cyclosporine (CsA) to tacrolimus (TAC) is reported. PATIENTS AND METHODS Fifteen patients (men age 42 +/- 11 years) after… (More)

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