Conversion from cyclosporine to azathioprine in renal graft recipients.

  title={Conversion from cyclosporine to azathioprine in renal graft recipients.},
  author={Allan S. Macdonald and Philip Belitsky and Rajan Gupta and Hinrich Bitter-Suermann and Robert L. Campbell and Amnon M. Cohen and Susan Lannon},
  journal={Transplantation proceedings},
  volume={17 4},
Only one of six patients in whom a clinical diagnosis of rejection was confirmed by both biopsy and FNA benefited from a switch from cyclosporine to azathioprine. Nine patients, in whom nephrotoxicity and rejection could not be separated and in whom the biopsy was positive but the FNA negative, improved when converted to cyclosporine. This improvement was, however, followed by subsequent rejection episodes in four of these patients. This study suggests caution in changing from CsA therapy in… CONTINUE READING

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