Converging effects of Ginkgo biloba extract at the level of transmitter release, NMDA and sodium currents and dendritic spikes.

@article{Szsz2008ConvergingEO,
  title={Converging effects of Ginkgo biloba extract at the level of transmitter release, NMDA and sodium currents and dendritic spikes.},
  author={Bernadett K. Sz{\'a}sz and Nora Lenkey and Albert M. I. Barth and Arpad Mike and Zsolt Somogyv{\'a}ri and Orsolya Farkas and Bal{\'a}zs Lendvai},
  journal={Planta medica},
  year={2008},
  volume={74 10},
  pages={
          1235-9
        }
}
In this study, an attempt was made to integrate the effects of GINKGO BILOBA extract (GBE) in different experimental systems (IN VITRO cochlea, brain slice preparations and cortical cell culture) to elucidate whether these processes converge to promote neuroprotection or interfere with normal neural function. GBE increased the release of dopamine in the cochlea. NMDA-evoked currents were dose-dependently inhibited by rapid GBE application in cultured cortical cells. GBE moderately inhibited Na… Expand
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