Converging catabolism of 2,4,6-trinitrophenol (picric acid) and 2,4-dinitrophenol by Nocardioides simplex FJ2-1A

@article{Ebert2004ConvergingCO,
  title={Converging catabolism of 2,4,6-trinitrophenol (picric acid) and 2,4-dinitrophenol by Nocardioides simplex FJ2-1A},
  author={S. Ebert and P. Fischer and H. Knackmuss},
  journal={Biodegradation},
  year={2004},
  volume={12},
  pages={367-376}
}
Initial F420-dependent hydrogenation of 2,4,6-trinitrophenol(picric acid) generated the hydride σ-complex of picrate and finally the dihydride complex.With 2,4-dinitrophenol the hydride σ-complex of 2,4-dinitrophenolis generated. The hydride transferring enzyme system showed activity against several substituted2,4-dinitrophenols but not with mononitrophenols. A Km-value of0.06 mM of the hydride transfer for picrate as substrate was found. The pH optimaof the NADPH-dependent F420 reductase and… Expand
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