Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells.

Abstract

Estrogen receptors display high levels of promiscuity in accommodating a wide range of ligand structures, but the functional consequence of changing receptor conformations in complex with distinct agonists is highly controversial. To determine variations in the transactivation capacity induced by different estrogenic agonists, we assessed global… (More)

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