Convergent evolution of heat-inducibility during subfunctionalization of the Hsp70 gene family

  title={Convergent evolution of heat-inducibility during subfunctionalization of the Hsp70 gene family},
  author={Sascha Krenek and Martin Schlegel and Thomas U. Berendonk},
  booktitle={BMC Evolutionary Biology},
Heat-shock proteins of the 70 kDa family (Hsp70s) are essential chaperones required for key cellular functions. In eukaryotes, four subfamilies can be distinguished according to their function and localisation in different cellular compartments: cytosol, endoplasmic reticulum, mitochondria and chloroplasts. Generally, multiple cytosol-type Hsp70s can be found in metazoans that show either constitutive expression and/or stress-inducibility, arguing for the evolution of different tasks and… CONTINUE READING


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