Convergent evolution of gene circuits

@article{Conant2003ConvergentEO,
  title={Convergent evolution of gene circuits},
  author={Gavin C. Conant and Andreas Wagner},
  journal={Nature Genetics},
  year={2003},
  volume={34},
  pages={264-266}
}
Convergent evolution is a potent indicator of optimal design. We show here that convergent evolution occurs in genetic networks. Specifically, we show that multiple types of transcriptional regulation circuitry in Escherichia coli and the yeast Saccharomyces cerevisiae have evolved independently and not by duplication of one or a few ancestral circuits. 
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