Convergent and divergent development among M cell lineages in mouse mucosal epithelium.

@article{Wang2011ConvergentAD,
  title={Convergent and divergent development among M cell lineages in mouse mucosal epithelium.},
  author={Jing Wang and Veronica Gusti and A Prasanth Saraswati and David D. Lo},
  journal={Journal of immunology},
  year={2011},
  volume={187 10},
  pages={
          5277-85
        }
}
M cells are specialized epithelial cells mediating immune surveillance of the mucosal lumen by transepithelial delivery of Ags to underlying dendritic cells (DC). At least three M cell phenotypes are known in the airways and intestine, but their developmental relationships are unclear. We used reporter transgenic mouse strains to follow the constitutive development of M cell subsets and their acute induction by cholera toxin (CT). M cells overlying intestinal Peyer's patches (PPs), isolated… CONTINUE READING
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