Convergent Transcription Induces Dynamic DNA Methylation at disiRNA Loci

@inproceedings{Dang2013ConvergentTI,
  title={Convergent Transcription Induces Dynamic DNA Methylation at disiRNA Loci},
  author={Yunkun Dang and Liande Li and Wei Guo and Zhihong Xue and Yi Liu},
  booktitle={PLoS genetics},
  year={2013}
}
Cytosine methylation of DNA is an important epigenetic gene silencing mechanism in plants, fungi, and animals. In the filamentous fungus Neurospora crassa, nearly all known DNA methylations occur in transposon relics and repetitive sequences, and DNA methylation does not depend on the canonical RNAi pathway. disiRNAs are Dicer-independent small non-coding RNAs that arise from gene-rich part of the Neurospora genome. Here we describe a new type of DNA methylation that is associated with the… CONTINUE READING
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