Convergent RANK- and c-Met-Mediated Signaling Components Predict Survival of Patients with Prostate Cancer: An Interracial Comparative Study

@inproceedings{Hu2013ConvergentRA,
  title={Convergent RANK- and c-Met-Mediated Signaling Components Predict Survival of Patients with Prostate Cancer: An Interracial Comparative Study},
  author={Peizhen Hu and Leland W. K. Chung and Dror Berel and Henry F. Frierson and Hua Guang Yang and Chun-yan Liu and Ruoxiang Wang and Qinlong Li and Andr{\'e} Rogatko and Haiyen E. Zhau},
  booktitle={PloS one},
  year={2013}
}
We reported (PLoS One 6 (12):e28670, 2011) that the activation of c-Met signaling in RANKL-overexpressing bone metastatic LNCaP cell and xenograft models increased expression of RANK, RANKL, c-Met, and phosphorylated c-Met, and mediated downstream signaling. We confirmed the significance of the RANK-mediated signaling network in castration resistant clinical human prostate cancer (PC) tissues. In this report, we used a multispectral quantum dot labeling technique to label six RANK and c-Met… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 30 references

Autocrine/ paracrine RANKL-RANK signaling promotes cancer bone metastasis and establishes premetastatic niche recruiting bystander cancer cells to participate in the metastatic process

GCY Chu, HE Zhau, R Wang, A Rogatko, X Feng
American Association for Cancer Research, • 2013
View 2 Excerpts

cancer metastasis : role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis

S Zhang, X Wang, S Iqbal, Y Wang, AO Osunkoya
Prostate • 2013

Tissue Biomarkers for Prostate Cancer Radiation Therapy

Current molecular medicine • 2012
View 1 Excerpt

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