Convergent Processing of Both Positive and Negative Motivational Signals by the VTA Dopamine Neuronal Populations

@inproceedings{Wang2011ConvergentPO,
  title={Convergent Processing of Both Positive and Negative Motivational Signals by the VTA Dopamine Neuronal Populations},
  author={Dong V Wang and Joe Z. Tsien},
  booktitle={PloS one},
  year={2011}
}
Dopamine neurons in the ventral tegmental area (VTA) have been traditionally studied for their roles in reward-related motivation or drug addiction. Here we study how the VTA dopamine neuron population may process fearful and negative experiences as well as reward information in freely behaving mice. Using multi-tetrode recording, we find that up to 89% of the putative dopamine neurons in the VTA exhibit significant activation in response to the conditioned tone that predict food reward, while… CONTINUE READING

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References

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Multiple dopamine functions at different time courses.

Annual review of neuroscience • 2007
View 5 Excerpts
Highly Influenced

Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 2 Excerpts

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