Convergence of adipocyte hypertrophy, telomere shortening and hypoadiponectinemia in obese subjects and in patients with type 2 diabetes.

@article{Monickaraj2012ConvergenceOA,
  title={Convergence of adipocyte hypertrophy, telomere shortening and hypoadiponectinemia in obese subjects and in patients with type 2 diabetes.},
  author={F. Monickaraj and K. Gokulakrishnan and P. Prabu and C. Sathishkumar and R. Anjana and J. S. Rajkumar and V. Mohan and M. Balasubramanyam},
  journal={Clinical biochemistry},
  year={2012},
  volume={45 16-17},
  pages={
          1432-8
        }
}
  • F. Monickaraj, K. Gokulakrishnan, +5 authors M. Balasubramanyam
  • Published 2012
  • Medicine
  • Clinical biochemistry
  • OBJECTIVE Although telomere shortening has been linked with type 2 diabetes and most variables of adiposity, a shortcoming of such studies is the measurement of telomere length in leukocytes. Therefore, we tested the association among adipocyte cell size, telomere length (both subcutaneous and visceral adipose tissue) and systemic levels of adiponectin in obese subjects and patients with type 2 diabetes compared to control subjects. METHODS Human subcutaneous and visceral adipose tissues were… CONTINUE READING
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