Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-treated Yeast Cells*

@inproceedings{Iemantaviius2014ConvergenceOU,
  title={Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-treated Yeast Cells*
},
  author={Vytautas Ie{\vs}mantavi{\vc}ius and Brian Tate Weinert and Chunaram Choudhary},
  booktitle={Molecular & cellular proteomics : MCP},
  year={2014}
}
The target of rapamycin (TOR) kinase senses the availability of nutrients and coordinates cellular growth and proliferation with nutrient abundance. Inhibition of TOR mimics nutrient starvation and leads to the reorganization of many cellular processes, including autophagy, protein translation, and vesicle trafficking. TOR regulates cellular physiology by modulating phosphorylation and ubiquitylation signaling networks; however, the global scope of such regulation is not fully known. Here, we… CONTINUE READING
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