Convergence of CD19 and B cell antigen receptor signals at MEK1 in the ERK2 activation cascade.

Abstract

CD19 plays a critical role in regulating B cell responses to Ag. We have studied the mechanism by which coligation of CD19 and the B cell Ag receptor, membrane Ig (mIg), augments signal transduction, including synergistic enhancement of release of intracellular Ca2+ and extracellular signal-regulated protein kinase 2 (ERK2) activation, in Daudi human B… (More)

Topics

  • Presentations referencing similar topics