Convenient synthesis of 7′ and 6′-bromo-d-tryptophan and their derivatives by enzymatic optical resolution using d-aminoacylase

@article{KondaYamada2002ConvenientSO,
  title={Convenient synthesis of 7′ and 6′-bromo-d-tryptophan and their derivatives by enzymatic optical resolution using d-aminoacylase},
  author={Yaeko Konda-Yamada and Chiharu Okada and K. Yoshida and Yasuyuki Umeda and S. Arima and N. Sato and T. Kai and H. Takayanagi and Y. Harigaya},
  journal={Tetrahedron},
  year={2002},
  volume={58},
  pages={7851-7861}
}
Abstract Compounds 7′ and 6′-bromo- d -tryptophan ( 1 and 2 ) which are important derivatives for the synthesis of the chloropeptin and kistamycin A, respectively, were conveniently synthesized by optical resolution from N-acetyl-7′ and 6′-bromo- dl -tryptophan ((RS)-5 and (RS)-14 ) using d -aminoacylase. 
A simple, modular synthesis of C4-substituted tryptophan derivatives.
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