Convection-enhanced delivery of maghemite nanoparticles: Increased efficacy and MRI monitoring.

Abstract

Convection-enhanced drug delivery (CED) is a novel approach to delivering drugs into brain tissue. Drugs are delivered continuously via a catheter, enabling large volume distributions of high drug concentrations with minimum systemic toxicity. Previously we demonstrated that CED formation/extent of small molecules may be significantly improved by increasing… (More)
DOI: 10.1215/15228517-2008-002

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