Convection-enhanced delivery for the treatment of brain tumors.

  title={Convection-enhanced delivery for the treatment of brain tumors.},
  author={Waldemar Debinski and Stephen B Tatter},
  journal={Expert review of neurotherapeutics},
  volume={9 10},
The brain is highly accessible for nutrients and oxygen, however delivery of drugs to malignant brain tumors is a very challenging task. Convection-enhanced delivery (CED) has been designed to overcome some of the difficulties so that pharmacological agents that would not normally cross the BBB can be used for treatment. Drugs are delivered through one to several catheters placed stereotactically directly within the tumor mass or around the tumor or the resection cavity. Several classes of… CONTINUE READING
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Canine brain tumors overexpress common molecular denominators of human high - grade astrocytomas

  • W Debinski, DM Gibo, J Wykosky, C Stanton, J Rosmeissl, J Robertson
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