Conus venoms: a rich source of novel ion channel-targeted peptides.

@article{Terlau2004ConusVA,
  title={Conus venoms: a rich source of novel ion channel-targeted peptides.},
  author={Heinrich Terlau and Baldomero M. Olivera},
  journal={Physiological reviews},
  year={2004},
  volume={84 1},
  pages={
          41-68
        }
}
The cone snails (genus Conus) are venomous marine molluscs that use small, structured peptide toxins (conotoxins) for prey capture, defense, and competitor deterrence. Each of the 500 Conus can express approximately 100 different conotoxins, with little overlap between species. An overwhelming majority of these peptides are probably targeted selectively to a specific ion channel. Because conotoxins discriminate between closely related subtypes of ion channels, they are widely used as… 

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