Controlling viral capsid assembly with templating.

  title={Controlling viral capsid assembly with templating.},
  author={Michael F Hagan},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  volume={77 5 Pt 1},
We develop coarse-grained models that describe the dynamic encapsidation of functionalized nanoparticles by viral capsid proteins. We find that some forms of cooperative interactions between protein subunits and nanoparticles can dramatically enhance rates and robustness of assembly, as compared to the spontaneous assembly of subunits into empty capsids… CONTINUE READING