Controlling the proportion of false positives in multiple dependent tests.

  title={Controlling the proportion of false positives in multiple dependent tests.},
  author={Rohan L. Fernando and Dan Nettleton and Bruce R. Southey and Jack C M Dekkers and Max F. Rothschild and Morris Soller},
  volume={166 1},
Genome scan mapping experiments involve multiple tests of significance. Thus, controlling the error rate in such experiments is important. Simple extension of classical concepts results in attempts to control the genomewise error rate (GWER), i.e., the probability of even a single false positive among all tests. This results in very stringent comparisonwise error rates (CWER) and, consequently, low experimental power. We here present an approach based on controlling the proportion of false… CONTINUE READING
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