Controlling the porosity of fibrous scaffolds by modulating the fiber diameter and packing density.

@article{Soliman2011ControllingTP,
  title={Controlling the porosity of fibrous scaffolds by modulating the fiber diameter and packing density.},
  author={Sherif Soliman and Shilpa Sant and Jason William Nichol and Masoud Khabiry and Enrico Traversa and Ali Khademhosseini},
  journal={Journal of biomedical materials research. Part A},
  year={2011},
  volume={96 3},
  pages={566-74}
}
Porosity has been shown to be a key determinant of the success of tissue engineered scaffolds. A high degree of porosity and an appropriate pore size are necessary to provide adequate space for cell spreading and migration as well as to allow for proper exchange of nutrients and waste between the scaffold and the surrounding environment. Electrospun scaffolds offer an attractive approach for mimicking the natural extracellular matrix (ECM) for tissue engineering applications. The efficacy of… CONTINUE READING

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