Controlling the higher-order structure of giant DNA molecules.


Giant DNA molecules of size greater than several kbp adopt an elongated coil conformation in aqueous solution. On addition of various kinds of condensing agents, the giant DNA molecules fold into a compact state. With multivalent cations, individual DNA molecules show large discrete transitions between the elongated and compact states. Similarly, with the… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.