Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts.

@article{Bhatia1997ControllingCI,
  title={Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts.},
  author={Sangeeta N. Bhatia and Martin L. Yarmush and Mehmet Toner},
  journal={Journal of biomedical materials research},
  year={1997},
  volume={34 2},
  pages={
          189-99
        }
}
The repair or replacement of damaged tissues using in vitro strategies has focused on manipulation of the cell environment by modulation of cell-extracellular matrix interactions, cell-cell interactions, or soluble stimuli. Many of these environmental influences are easily controlled using macroscopic techniques; however, in co-culture systems with two or more cell types, cell-cell interactions have been difficult to manipulate precisely using similar methods. Although microfabrication has been… CONTINUE READING
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