Controlling cell growth and survival through regulated nutrient transporter expression.

@article{Edinger2007ControllingCG,
  title={Controlling cell growth and survival through regulated nutrient transporter expression.},
  author={Aimee L Edinger},
  journal={The Biochemical journal},
  year={2007},
  volume={406 1},
  pages={
          1-12
        }
}
  • A. Edinger
  • Published 15 August 2007
  • Biology, Environmental Science
  • The Biochemical journal
Although all cells depend upon nutrients they acquire from the extracellular space, surprisingly little is known about how nutrient uptake is regulated in mammalian cells. Most nutrients are brought into cells by means of specific transporter proteins. In yeast, the expression and trafficking of a wide variety of nutrient transporters is controlled by the TOR (target of rapamycin) kinase. Consistent with this, recent studies in mammalian cells have shown that mTOR (mammalian TOR) and the… 
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