Controlling biological networks by time-delayed signals.

  title={Controlling biological networks by time-delayed signals.},
  author={G{\'a}bor Orosz and Jeff Moehlis and Richard M. Murray},
  journal={Philosophical transactions. Series A, Mathematical, physical, and engineering sciences},
  volume={368 1911},
This paper describes the use of time-delayed feedback to regulate the behaviour of biological networks. The general ideas on specific transcriptional regulatory and neural networks are demonstrated. It is shown that robust yet tunable controllers can be constructed that provide the biological systems with model-engineered inputs. The results indicate that time delay modulation may serve as an efficient biocompatible control tool. 
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