Controlling Size in Multicellular Organs: Focus on the Leaf

  title={Controlling Size in Multicellular Organs: Focus on the Leaf},
  author={Hirokazu Tsukaya},
  journal={PLoS Biology},
  pages={177 - 184}
Unsolved Mystery L eaf size depends on cell number and size. However, leaves are not simply the sum of cell size and number; rather, they are under the control of an unknown, organ-wide integration system. The existence of such a system is strongly suggested by two mysterious phenomena: compensation and high-ploidy syndrome. Compensation is characterized by cell enlargement triggered by a significant decrease in cellular proliferation, while plants with high-ploidy syndrome have more than eight… CONTINUE READING
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Arabidopsis BIN 4 , a novel component of the plant DNA topoisomerase VI complex , promotes organ growth by endoreduplication

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