Controlled trials of inositol in psychiatry
@article{Levine1997ControlledTO, title={Controlled trials of inositol in psychiatry}, author={J. Levine}, journal={European Neuropsychopharmacology}, year={1997}, volume={7}, pages={147-155} }
Inositol is a simple polyol precursor in a second messenger system important in the brain. Cerebrospinal fluid inositol has been reported as decreased in depression. A double-blind controlled trial of 12 g daily of inositol in 28 depressed patients for four weeks was performed. Significant overall benefit for inositol compared to placebo was found at week 4 on the Hamilton Depression Scale. No changes were noted in hematology, kidney or liver function. Since many antidepressants are effective… CONTINUE READING
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Paper Mentions
Interventional Clinical Trial
This is an open trial which seeks to determine safety and tolerability of using inositol for
children and adolescents with bipolar disorder and comorbid anxiety disorders with… Expand
Conditions | Anxiety, Anxiety Disorders, Bipolar Disorder |
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Intervention | Drug |
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