Controlled trial of sulpiride in chronic schizophrenic patients.

@article{Edwards1980ControlledTO,
  title={Controlled trial of sulpiride in chronic schizophrenic patients.},
  author={J. Edwards and J. R. Alexander and M. S. Alexander and A. Gordon and T. Zutchi},
  journal={The British journal of psychiatry : the journal of mental science},
  year={1980},
  volume={137},
  pages={
          522-9
        }
}
In a double-blind comparative trial of sulpiride (600-1,800 mg/day) and trifluoperazine (15-45 mg/day) in 38 chronic schizophrenic patients, ratings of therapeutic results and unwanted effects were made at two-weekly interviews during the six weeks treatment period. The results show that sulpiride has neuroleptic properties and a spectrum of therapeutic activity similar to that of trifluoperazine. There was an association between plasma sulpiride levels and therapeutic response after four weeks… Expand
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