Controlled trial of imipramine for chronic low back pain.

  title={Controlled trial of imipramine for chronic low back pain.},
  author={J M Alcoff and Elizabeth O Jones and Petra Rust and Robert Newman},
  journal={The Journal of family practice},
  volume={14 5},
Chronic low back pain is a common problem that has been noted in several studies to exist as a component of masked depression. To determine the usefulness of imipramine in the treatment of chronic low back pain, either by a direct action or indirectly via resolution of a depressive equivalent, 50 consecutive patients were entered into a controlled trail that employed serum imipramine and desipramine levels and Beck depression questionnaires. Forty-one patients completed the study, and 48 were… CONTINUE READING

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