Controlled study of citrate effects and response to i.v. calcium administration during allogeneic peripheral blood progenitor cell donation.

@article{Bolan2002ControlledSO,
  title={Controlled study of citrate effects and response to i.v. calcium administration during allogeneic peripheral blood progenitor cell donation.},
  author={Charles D. Bolan and Stacey A Cecco and Robert A. Wesley and M J Horne and Yu Ying Yau and Alan T Remaley and Richard W. Childs and A. J. Barrett and Nadja N. Rehak and Susan F. Leitman},
  journal={Transfusion},
  year={2002},
  volume={42 7},
  pages={935-46}
}
BACKGROUND Leukapheresis procedures are generally performed at citrate anticoagulation rates extrapolated from shorter plateletpheresis procedures. However, neither the metabolic effects nor the management of associated symptoms have been critically evaluated during leukapheresis in healthy donors. STUDY DESIGN AND METHODS Symptom assessments (n = 315) and laboratory analyses (n = 49) were performed during 244 procedures performed with and 71 without prophylactic calcium (Ca) chloride or Ca… CONTINUE READING
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