Controlled spacing of cationic gold nanoparticles by nanocrown RNA.

  title={Controlled spacing of cationic gold nanoparticles by nanocrown RNA.},
  author={Alexey Y. Koyfman and Gary B Braun and Sergei Magonov and Arkadiusz Chworoś and Norbert O Reich and Luc Jaeger},
  journal={Journal of the American Chemical Society},
  volume={127 34},
Using atomic force microscopy, we describe the linear arrangement of cationic gold nanoparticles directed by programmable self-assembling RNA ladders and demonstrate that the regular spacing of nanoparticles is controlled by the RNA architecture acting as nanocrown scaffoldings. Thus, precise positioning of molecular components can be accomplished with RNA not only through electrostatic but also via size and shape recognitions. 
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