Controlled release of heparin from polypyrrole-poly(vinyl alcohol) assembly by electrical stimulation.

@article{Li2005ControlledRO,
  title={Controlled release of heparin from polypyrrole-poly(vinyl alcohol) assembly by electrical stimulation.},
  author={Yali Li and Koon Gee Neoh and E. T. Kang},
  journal={Journal of biomedical materials research. Part A},
  year={2005},
  volume={73 2},
  pages={171-81}
}
A surface modification technique was developed for the covalent immobilization of poly(vinyl alcohol) (PVA)-heparin hydrogel onto electrically conductive polypyrrole (PPY) film with the objective of achieving controlled release of heparin. First, aldehyde groups were introduced onto PPY film through poly(ethylene glycol) monomethacrylate graft copolymerization and subsequent oxidation in acetic anhydride and dimethyl sulfoxide mixture. Then, the prepared PVA-heparin hydrogel was cast onto the… CONTINUE READING

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