Controlled-release and local delivery of therapeutic antibodies.

  title={Controlled-release and local delivery of therapeutic antibodies.},
  author={David W. Grainger},
  journal={Expert opinion on biological therapy},
  volume={4 7},
Human and humanised antibodies are now poised to become a major new class of protein-based therapeutic agents. A significant fraction of new drugs in clinical testing (approximately 20% in 2002) are antibody classes. Monoclonal antibodies (mAbs) with high affinities against newly discovered disease targets, both cellularly and extracellularly, are now clinically proven to elicit high bioactivities against numerous diseases, including tumours, infections, asthma, inflammation, arthritis and… CONTINUE READING