Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.

  title={Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.},
  author={Doncho V. Zhelev and Abdullatif M Alteraifi and David Chodniewicz},
  journal={Biophysical journal},
  volume={87 1},
The formation of pseudopods and lamellae after ligation of chemoattractant sensitive G-protein coupled receptors (GPCRs) is essential for chemotaxis. Here, pseudopod extension was stimulated with chemoattractant delivered from a micropipet. The chemoattractant diffusion and convection mass transport were considered, and it is shown that when the delivery of chemoattractant was limited by diffusion there was a strong chemoattractant gradient along the cell surface. The diffusion-limited delivery… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 34 extracted citations

Shear-induced resistance to neutrophil activation via the formyl peptide receptor

2011 IEEE 37th Annual Northeast Bioengineering Conference (NEBEC) • 2011
View 12 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…