Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.

@article{Zhelev2004ControlledPE,
  title={Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.},
  author={Doncho V. Zhelev and Abdullatif M Alteraifi and David Chodniewicz},
  journal={Biophysical journal},
  year={2004},
  volume={87 1},
  pages={688-95}
}
The formation of pseudopods and lamellae after ligation of chemoattractant sensitive G-protein coupled receptors (GPCRs) is essential for chemotaxis. Here, pseudopod extension was stimulated with chemoattractant delivered from a micropipet. The chemoattractant diffusion and convection mass transport were considered, and it is shown that when the delivery of chemoattractant was limited by diffusion there was a strong chemoattractant gradient along the cell surface. The diffusion-limited delivery… CONTINUE READING

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