Controlled gene activation and inactivation in the mouse.

  title={Controlled gene activation and inactivation in the mouse.},
  author={Moises Mallo},
  journal={Frontiers in bioscience : a journal and virtual library},
  • Moises Mallo
  • Published 2006 in
    Frontiers in bioscience : a journal and virtual…
The emergence of techniques that allow fine manipulation of gene expression in the mouse have changed the way biomedically relevant processes are studied, as they allow their analysis in the living animal. In addition, this has opened the possibility to generate animal models for several human diseases, which are useful both for understanding the disease' s physiopathological mechanisms and for the eventual evaluation of novel therapeutic approaches. Many of the gene manipulation systems… CONTINUE READING

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