Controlled dual release of basic fibroblast growth factor and indomethacin from heparin-conjugated polymeric micelle.

@article{Lee2008ControlledDR,
  title={Controlled dual release of basic fibroblast growth factor and indomethacin from heparin-conjugated polymeric micelle.},
  author={Jung Seok Lee and Jin Woo Bae and Yoon Ki Joung and Seung Jin Lee and Dong Keun Han and Ki Dong Park},
  journal={International journal of pharmaceutics},
  year={2008},
  volume={346 1-2},
  pages={57-63}
}
This work describes the development of heparinized polymeric micelle as a novel injectable carrier for the dual drug delivery that can simultaneously release basic fibroblast growth factor (bFGF) and indomethacin (IMC), which can promote the regeneration of damaged tissue and prevent the inflammatory response after implantation. Tetronic-PCL-heparin for the… CONTINUE READING