Controlled and targeted tumor chemotherapy by ultrasound-activated nanoemulsions/microbubbles.

@article{Rapoport2009ControlledAT,
  title={Controlled and targeted tumor chemotherapy by ultrasound-activated nanoemulsions/microbubbles.},
  author={Natalya Y Rapoport and Anne M. Kennedy and Jill Shea and Courtney L. Scaife and K Nam},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2009},
  volume={138 3},
  pages={268-76}
}
The paper reports the results of nanotherapy of ovarian, breast, and pancreatic cancerous tumors by paclitaxel-loaded nanoemulsions that convert into microbubbles locally in tumor tissue under the action of tumor-directed therapeutic ultrasound. Tumor accumulation of nanoemulsions was confirmed by ultrasound imaging. Dramatic regression of ovarian, breast, and orthotopic pancreatic tumors was observed in tumor therapy through systemic injections of drug-loaded nanoemulsions combined with… CONTINUE READING

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