Controlled Delivery of Diphtheria Toxoid Using Biodegradable Poly(D,L-Lactide) Microcapsules

@article{Singh1991ControlledDO,
  title={Controlled Delivery of Diphtheria Toxoid Using Biodegradable Poly(D,L-Lactide) Microcapsules},
  author={Manmohan Singh and Amarjit Kumar Singh and Gursharan Prasad Talwar},
  journal={Pharmaceutical Research},
  year={1991},
  volume={8},
  pages={958-961}
}
Diphtheria toxoid, which is an important vaccine in the expanded program of immunization (EPI) in the developing countries, was microencapsulated using poly(D,L,-lactide) of 49,000 molecular weight and the in-water drying technique. The microcapsules were subjected to an in vitro antigen release study using a sensitive enzyme-linked immunosorbent assay… CONTINUE READING