• Corpus ID: 237562960

Controlled Comparison of Simulated Hemodynamics across Tricuspid and Bicuspid Aortic Valves

  title={Controlled Comparison of Simulated Hemodynamics across Tricuspid and Bicuspid Aortic Valves},
  author={Alexander D. Kaiser and Rohan Shad and Nicole K Schiavone and William Hiesinger and Alison L. Marsden},
Bicuspid aortic valve is the most common congenital heart defect, affecting 1-2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both hemodynamic and genetic factors are believed to contribute to dilation, yet the precise mechanism underlying this progression remains under debate. Controlled comparisons of hemodynamics in patients with different forms of bicuspid valve disease are challenging because of confounding… 
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