Control of yeast retrotransposons mediated through nucleoporin evolution

@inproceedings{Rowley2018ControlOY,
  title={Control of yeast retrotransposons mediated through nucleoporin evolution},
  author={Paul A Rowley and Kurt Patterson and Suzanne B. Sandmeyer and Sara L Sawyer},
  booktitle={PLoS genetics},
  year={2018}
}
Yeasts serve as hosts to several types of genetic parasites. Few studies have addressed the evolutionary trajectory of yeast genes that control the stable co-existence of these parasites with their host cell. In Saccharomyces yeasts, the retrovirus-like Ty retrotransposons must access the nucleus. We show that several genes encoding components of the yeast nuclear pore complex have experienced natural selection for substitutions that change the encoded protein sequence. By replacing these S… CONTINUE READING
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